Does radiofrequency ablation improve CMR LVEF compared to a rate control strategy in patients with persistent atrial fibrillation and advanced heart failure?
Patients with persistent atrial fibrillation, advanced heart failure, and severe left ventricular systolic dysfunction
Radiofrequency ablation (RFA)
Strategy of rate control
Left ventricular ejection fraction (LVEF) measured by cardiac magnetic resonance (CMR)surrogate
In patients with persistent atrial fibrillation and advanced heart failure, radiofrequency ablation did not improve CMR LVEF compared to rate control and was associated with significant serious complications.
RFA resulted in long-term restoration of sinus rhythm in only 50% of patients. RFA did not improve CMR LVEF compared with a strategy of rate control. RFA did improve radionuclide LVEF but did not improve other secondary outcomes and was associated with a significant rate of serious complications.
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Michael R. MacDonald
Derek T. Connelly
Nathaniel M. Hawkins
Heart
ENLIGHTEN (Jurnal Bimbingan dan Konseling Islam)
University of Glasgow
Edinburgh Royal Infirmary
Glasgow Royal Infirmary
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MacDonald et al. (Thu,) studied this question.
www.synapsesocial.com/papers/69d56c3d75589c71d767cd13 — DOI: https://doi.org/10.1136/hrt.2010.207340
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