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This cohort study found a 28.8% recurrence rate of the same irAE associated with the discontinuation of ICI therapy after a rechallenge with the same ICI. Resuming ICI therapy could be considered for select patients, with appropriate monitoring and use of standard treatment algorithms to identify and treat toxic effects.
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Dolladille et al. (Thu,) studied this question.
www.synapsesocial.com/papers/69d56c3f75589c71d767cd25 — DOI: https://doi.org/10.1001/jamaoncol.2020.0726
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:
Charles Dolladille
Stéphane Éderhy
Marion Sassier
JAMA Oncology
Inserm
Assistance Publique – Hôpitaux de Paris
Aix-Marseille Université
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