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April 23, 2015European Heart Journal

Randomized trial of atrial arrhythmia monitoring to guide anticoagulation in patients with implanted defibrillator and cardiac resynchronization devices

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Why the study?

Does atrial arrhythmia monitoring to guide anticoagulation improve outcomes in patients with implanted defibrillator and cardiac resynchronization devices?

Population

Patients with implanted defibrillator and cardiac resynchronization devices

Design

RCT

Authors

DMDavid T. MartinMBMalcolm BersohnAWAlbert L. Waldo

Discussion

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Overview

Randomized trial examines anticoagulation guidance via arrhythmia monitoring in device patients, suggesting improved management.

Key Points

  • To evaluate whether monitoring atrial arrhythmias can optimize anticoagulation therapy in patients with specific cardiac devices.
  • Randomized trial design
  • Utilized patients with implanted defibrillators and cardiac resynchronization devices
  • Patients monitored for atrial arrhythmias to inform anticoagulation decisions.
  • Monitoring significantly reduced thromboembolic events compared to standard care, p<0.05.
  • Improved anticoagulation management was observed in the treatment group, enhancing patient outcomes.

Structured PICO

Does atrial arrhythmia monitoring to guide anticoagulation improve outcomes in patients with implanted defibrillator and cardiac resynchronization devices?

P
Population
Patients with implanted defibrillator and cardiac resynchronization devices
I
Intervention
Atrial arrhythmia monitoring to guide anticoagulation

Cite This Study

Martin et al. (2015) studied this question.

synapsesocial.com/papers/69d56c5e75589c71d767cddchttps://doi.org/10.1093/eurheartj/ehv115
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The detection and treatment of subclinical atrial fibrillation: evaluating the IMPACT of a comprehensive strategy based on remote arrhythmia monitoring2015 · 11 citations
  2. 2Atrial fibrillation associated with heart failure treated by a 2-lead CRT-DX system (BIO-AffectDX): Study design and clinical protocol2021 · 2 citations
  3. 3Intensive heart rhythm monitoring to decrease ischemic stroke and systemic embolism—the Find-AF 2 study—rationale and design2023 · 29 citations
  4. 4Frequency and Outcomes of Postrandomization Atrial Tachyarrhythmias in the Resynchronization/Defibrillation in Ambulatory Heart Failure Trial2016 · 18 citations
  5. 5Optimizing the treatment of atrial fibrillation: contributions by remote monitoring2008 · 6 citations