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November 1, 2004Psychosomatic Medicine1,371 citations

Depression as a Risk Factor for Mortality in Patients With Coronary Heart Disease: A Meta-analysis

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JBJürgen BarthMSM. SchumacherCHChristoph Herrmann‐Lingen

Key Points

  • To evaluate the impact of depressive symptoms and clinical depression on mortality in patients diagnosed with coronary heart disease.
  • Conducted a meta-analysis synthesizing primary studies examining depression and mortality outcomes in coronary heart disease patients.

Structured PICO

Does depression increase mortality in patients with coronary heart disease?

P
Population
Patients with Coronary Heart Disease (CHD)
I
Intervention
Depressive symptoms and clinical depression
O
Outcome
Mortalityhard clinical

Depression is a relevant risk factor for mortality in patients with coronary heart disease.

Limitations

  • Heterogeneity of the results in the primary studies
  • No clear evidence whether self-report or clinical interview is the more precise predictor

Abstract

Depressive symptoms and clinical depression have an unfavorable impact on mortality in CHD patients. The results are limited by heterogeneity of the results in the primary studies. There is no clear evidence whether self-report or clinical interview is the more precise predictor. Nevertheless, depression has to be considered a relevant risk factor in patients with CHD.

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Cite This Study

Barth et al. (2004) studied this question.

synapsesocial.com/papers/69d56d3675589c71d767d008https://doi.org/10.1097/01.psy.0000146332.53619.b2
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