Does aspirin-free P2Y12 inhibitor monotherapy without initial DAPT improve safety and efficacy compared to standard DAPT strategies in patients with acute coronary syndrome or stable coronary artery disease after PCI?
Selected patients with acute coronary syndrome or stable coronary artery disease after percutaneous coronary intervention (PCI)
Aspirin-free P2Y12 inhibitor monotherapy without initial dual antiplatelet therapy (DAPT)
Standard DAPT strategies
While single-arm studies suggest aspirin-free P2Y12 inhibitor monotherapy immediately after PCI is feasible, its safety and efficacy compared to standard DAPT require further investigation.
Single-arm studies suggest the safety and feasibility of aspirin-free P2Y12 inhibitor monotherapy without initial DAPT after PCI in selected patients with acute coronary syndrome or stable coronary artery disease. However, the safety and efficacy of this aspirin-free approach compared with standard DAPT strategies following PCI still require further investigation.
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Shenglong Yu
Linjuan Guo
Huizhuang Guo
Heliyon
SHILAP Revista de lepidopterología
Guangzhou Medical University
Jiangxi Provincial People's Hospital
Panyu District Central Hospital
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Yu et al. (Thu,) studied this question.
www.synapsesocial.com/papers/69d572e975589c71d767e8fe — DOI: https://doi.org/10.1016/j.heliyon.2024.e35741