Efficacy of olanzapine for prophylaxis of delayed chemotherapy-induced nausea and vomiting in patients with breast cancer receiving dose-dense AC with a steroid-sparing regimen: a single-center pilot study

Puntos clave

• The research aims to evaluate the efficacy of olanzapine in preventing delayed nausea and vomiting caused by chemotherapy in breast cancer patients.
• Pilot study design conducted at a single center
• Included patients receiving dose-dense AC chemotherapy
• Used a steroid-sparing regimen for prophylaxis
• Measured nausea and vomiting outcomes post-chemotherapy
• Demonstrated a reduction in delayed nausea and vomiting events
• Indicated improved patient comfort during and after chemotherapy
• Showed potential for olanzapine as an effective prophylactic agent