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April 8, 2026Arthritis Care & Research0 citations

Biopsychosocial determinants of hand function and its trajectories over five years in patients with hand osteoarthritis

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AMAnnemiek V.E.M. Olde MeuleCMCoen van der MeulenJRJos Runhaar

Key Points

  • This research aims to explore the biopsychosocial factors that influence hand function and its changes over time in patients with osteoarthritis.
  • Used Latent Class Growth Analysis (LCGA) to identify patient groups based on hand function trajectories.
  • Studied patients with hand osteoarthritis over a five-year period to assess changes in function.
  • Analyzed the role of disease characteristics and psychosocial factors in determining hand function.
  • Identified four distinct patient groups based on hand function changes over five years.
  • Two of the groups exhibited a decline in hand function, highlighting significant variability in outcomes.
  • Hand function was significantly influenced by both structural damage and psychosocial factors.

Abstract

Hand function varies greatly in patients with hand OA. LCGA identified four longitudinal patient groups, of which two showed an unfavorable hand function course over 5 years. Hand function was characterized by disease characteristics, including structural damage and psychosocial determinants.

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Cite This Study

Meule et al. (2026) studied this question.

synapsesocial.com/papers/69d5f13674eaea4b11a7acd0https://doi.org/10.1002/acr.80055
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