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These data underline the fundamental importance of macrophage-derived CXCR3 ligands for the therapeutic efficacy of ICB and highlight the potential of manipulating this axis to enhance patient responses.
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Imran G. House
Peter Savas
Junyun Lai
Clinical Cancer Research
The University of Melbourne
Monash University
Peter MacCallum Cancer Centre
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House et al. (Mon,) studied this question.
www.synapsesocial.com/papers/69d6c45139aaaf0da5ab35a9 — DOI: https://doi.org/10.1158/1078-0432.ccr-19-1868