Haploview: análise e visualização de mapas de LD e haplótipos

Barrett et al. (qui,) estudaram essa questão.

www.synapsesocial.com/papers/69d809d505ee2ba81dbeec62 — DOI: https://doi.org/10.1093/bioinformatics/bth457

Also consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1. Association of the ADAM33 gene with asthma and bronchial hyperresponsiveness· 2002 · 1,099 citations
2. Linkage disequilibrium in the human genome· 2001 · 1,779 citations
3. Distribution of Recombination Crossovers and the Origin of Haplotype Blocks: The Interplay of Population History, Recombination, and Mutation· 2002 · 464 citations
4. The Fine-Scale Structure of Recombination Rate Variation in the Human Genome· 2004 · 1,025 citations
5. Haplotype tagging for the identification of common disease genes· 2001 · 1,177 citations