Primary hepatic Ewing's sarcoma was diagnosed in a 7-year-old boy with pulmonary and skeletal metastases, representing the youngest case described to date.
Case Report
No
7-year-old boy with primary hepatic Ewing's sarcoma
Diagnosis of primary hepatic Ewing's sarcoma
Reports the youngest known case of primary hepatic Ewing's sarcoma, highlighting the need to consider it in pediatric liver tumor differential diagnosis.
Ewing’s sarcoma (ES) is a rare malignant small round-cell tumor that usually arises in bone and only exceptionally originates in visceral organs. We report the case of a 7-year-old boy with primary hepatic ES, the youngest case described to date. Imaging revealed a large, solid hepatic mass with heterogeneous enhancement and extensive local vascular involvement, associated with pulmonary and skeletal metastases. Histology and immunohistochemistry (CD99 +, INI-1 +, NKX2.2 +, Ki-67 ≈ 60%) confirmed the diagnosis. This is the first Moroccan and the seventh case of primary hepatic ES reported in the literature, emphasizing the need to consider this entity in the differential diagnosis of pediatric liver tumors.
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Sarah Lembarki
Fatma ez zahrae El malki
Nazik Allali
Radiology Case Reports
Centre Hospitalier Ibn Sina
High-Tech Rabat-Agdal
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Lembarki et al. (Mon,) conducted a case report in Primary hepatic Ewing's sarcoma (n=1). Primary hepatic Ewing's sarcoma was diagnosed in a 7-year-old boy with pulmonary and skeletal metastases, representing the youngest case described to date.
www.synapsesocial.com/papers/69d8930e6c1944d70ce041b6 — DOI: https://doi.org/10.1016/j.radcr.2026.02.062