What question did this study set out to answer?

The research aims to assess how traditional and emerging lipid markers, specifically apoB, influence cardiovascular risk assessment in different age groups.

April 10, 2026Open Access

Traditional and Emerging Lipid Markers for Cardiovascular Risk Assessment in Young vs Older Adults

Key Points

The research aims to assess how traditional and emerging lipid markers, specifically apoB, influence cardiovascular risk assessment in different age groups.
Cohort study involving 10,519 adults
Evaluated the impact of adding apoB to PREVENT-estimated ASCVD risks
Compared risk reclassification between young and older adults
Adding apoB to risk assessments improved reclassification for younger adults
Modest improvements in cardiovascular risk assessment were observed
The clinical importance of these findings remains uncertain

Abstract

In this cohort study of 10 519 adults, adding apoB to PREVENT-estimated ASCVD risks was associated with improved risk reclassification, particularly in younger adults. However, the clinical importance of these modest improvements remains uncertain.

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Authors

Rui Tang

Jaejin An

Brandon K. Bellows

Journals

JAMA Network Open

Actions

Institutions

University of Minnesota

Northwestern University

Boston University

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Building similarity graph...

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Traditional and Emerging Lipid Markers for Cardiovascular Risk Assessment in Young vs Older Adults

Key Points

Abstract

Citation Network

Connected Papers

Discussion

Authors

Journals

Actions

Institutions

References and Citations

Citation Network

Connected Papers

Discussion

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