Plasma gelsolin as a potential biomarker for intrauterine inflammation in pregnant women with preterm premature rupture of membranes: A pilot study

Key Points

• This research aims to explore the correlation between plasma gelsolin levels and intrauterine inflammation in pregnant women experiencing preterm premature rupture of membranes.
• Pilot study design focusing on pregnant women with preterm premature rupture of membranes.
• Measurement of plasma gelsolin levels throughout the pregnancy progression.
• Evaluation of inflammation markers in correlation with plasma gelsolin.
• Plasma gelsolin levels decrease significantly with pregnancy progression.
• Lower gelsolin levels correlate with increased intrauterine inflammation.
• Gelsolin shows potential as a novel biomarker for inflammatory conditions.

Abstract