What question did this study set out to answer?

This research aims to investigate how gut microbes influence muscle texture in fish by regulating collagen synthesis.

April 10, 2026Open Access

Microbiota-gut-muscle axis shapes fish muscle texture by regulating collagen synthesis

Key Points

This research aims to investigate how gut microbes influence muscle texture in fish by regulating collagen synthesis.
Analyzed the role of gut microbes in tilapia muscle texture.
Examined SMAD2/3 acetylation as a mechanism for collagen synthesis.
Explored the gut-muscle axis's impact on muscle physiology.
Gut microbes were found to regulate collagen synthesis in tilapia.
SMAD2/3 acetylation was identified as a key pathway.
Findings suggest potential methods for improving muscle quality in fish production.

Abstract

The comprehensive results provided evidences that gut microbes regulated tilapia muscle texture through SMAD2/3 acetylation-driven collagen synthesis. This study expands our understanding of the multifaceted role of the gut-muscle axis in muscle physiology. Furthermore, our findings highlight that targeting gut microbiota and the downstream collagen synthesis pathway could be promising for manipulating muscle quality in animal production. Video Abstract.

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Authors

Zheng Wang

Lu-Kuan Li

Nannan Zhou

Journals

Microbiome

Actions

Institutions

East China Normal University

References and Citations

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Building similarity graph...

Analyzing shared references across papers

Microbiota-gut-muscle axis shapes fish muscle texture by regulating collagen synthesis

Key Points

Abstract

Citation Network

Connected Papers

Discussion

Authors

Journals

Actions

Institutions

References and Citations

Citation Network

Connected Papers

Discussion

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