What question did this study set out to answer?

This research aims to investigate the role of NDUFA10 in the progression of lung adenocarcinoma (LUAD).

April 10, 2026

NDUFA10: An Emerging Oncogenic Driver of Metastasis in LungAdenocarcinoma

Key Points

This research aims to investigate the role of NDUFA10 in the progression of lung adenocarcinoma (LUAD).
Experimental silencing of NDUFA10 in LUAD cells
Assessment of cell proliferation, migration, and invasion
Evaluation of the regulatory effects of circRAPGEF5 on NDUFA10
NDUFA10 silencing significantly suppresses LUAD cell proliferation
Migration and invasion of LUAD cells are inhibited upon NDUFA10 silencing
CircRAPGEF5 is identified as a regulator of NDUFA10, impacting LUAD progression

Abstract

Silencing NDUFA10 suppresses LUAD cell proliferation, migration, and invasion. The study suggested that circRAPGEF5 regulated NDUFA10 to facilitate the progression of LUAD.

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Authors

Tao Hu

Yun Chen

Yue Lu

Journals

Current Cancer Drug Targets

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Institutions

Wenzhou Medical University

First Affiliated Hospital of Wenzhou Medical University

Jinhua Academy of Agricultural Sciences

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NDUFA10: An Emerging Oncogenic Driver of Metastasis in LungAdenocarcinoma

Key Points

Abstract

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Discussion

Authors

Journals

Actions

Institutions

References and Citations

Citation Network

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