What question did this study set out to answer?

This research aims to understand how the airway microbiome affects respiratory infections related to tracheostomy in children.

April 10, 2026Open Access

Pediatric tracheostomy-associated respiratory infections: an evolving paradigm

Key Points

This research aims to understand how the airway microbiome affects respiratory infections related to tracheostomy in children.
Review of current advancements in TRAIN pathobiology
Assessment of airway microbiome during infections and wellness
Recommendation for antibiotic clinical trials for optimal treatment
Identified significant changes in airway microbiome during infections
Suggested a link between microbiome and host inflammation
Highlighted the need for clinical trials to improve treatment strategies

Abstract

With recent advances in TRAIN pathobiology, diagnosis, treatment, and prevention of TRAINs is undergoing a paradigm shift. Future translational research will define the airway microbiome during TRAINs and during wellness and its impact on host inflammation. Antibiotic clinical trials are needed to optimize treatment and prevention of TRAINs.

Connected Papers

Building similarity graph...

Analyzing shared references across papers

Discussion

Authors

John M. Morrison

Rebecca Steuart

Christopher J. Russell

Journals

Current Opinion in Pediatrics

Actions

Institutions

Johns Hopkins University

Johns Hopkins Medicine

Medical College of Wisconsin

References and Citations

Connected Papers

Building similarity graph...

Analyzing shared references across papers

Pediatric tracheostomy-associated respiratory infections: an evolving paradigm

Key Points

Abstract

Citation Network

Connected Papers

Discussion

Authors

Journals

Actions

Institutions

References and Citations

Citation Network

Connected Papers

Discussion

Cite this study

Also consider