Immune Checkpoint Inhibitor Esophagitis: Clinical and Endoscopic Presentation, Treatment Outcomes, and Complications

Key Points

• To evaluate the clinical and endoscopic features of immune checkpoint inhibitor esophagitis and its treatment outcomes.
• Reviewed cases of ICI esophagitis for clinical symptoms and endoscopic findings.
• Conducted biopsies to assess histologic inflammation.
• Analyzed treatment responses and complication rates.
• Esophagitis often appears normal endoscopically but requires biopsies for diagnosis.
• Symptoms generally respond well to treatment, yet inflammation may persist histologically.
• Severe complications of ICI esophagitis are rare but necessitate prompt recognition and targeted therapy.

Abstract