Co-inheritance of Hb Quong Sze and Thai deletion can result in falsely elevated HbA1c values.
Case Report
Does Hb QS-H disease interfere with HbA1c quantification across different detection platforms?
A patient with Hb Quong Sze Co-Inherited Thai Deletion (Hb QS-H disease)
HbA1c quantification using different detection platforms
Interference with HbA1c quantification (falsely elevated values)surrogate
Clinicians should be aware that Hb QS-H disease can cause falsely elevated HbA1c values, highlighting the need to consider hemoglobinopathies when HbA1c does not match the clinical picture.
Our findings demonstrate that Hb QS-H disease significantly interferes with HbA1c quantification, with methodological variability observed across different detection platforms.
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Qianqing Wei
Liang Liang
Zugui Li
Clinical Laboratory
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Wei et al. (Thu,) conducted a case report in Hb Quong Sze Co-Inherited Thai Deletion with Falsely Elevated HbA1c (n=1). Co-inheritance of Hb Quong Sze and Thai deletion can result in falsely elevated HbA1c values.
www.synapsesocial.com/papers/69d894526c1944d70ce053d4 — DOI: https://doi.org/10.7754/clin.lab.2025.250573