Long-term control of grade 3 intracranial solitary fibrous tumor achieved with pazopanib and stereotactic radiotherapy: illustrative case

Key Points

• This report aims to demonstrate the effectiveness of pazopanib and stereotactic radiotherapy in managing grade 3 intracranial solitary fibrous tumor.
• Presented an illustrative case of a patient with grade 3 intracranial solitary fibrous tumor.
• Administered pazopanib and utilized stereotactic radiotherapy for treatment.
• Emphasized the importance of flexible dosing and long-term surveillance.
• Notable response to pazopanib in reducing progression of visceral and bone metastases.
• Limited effect observed on intracranial disease, necessitating continued stereotactic irradiation.
• Long-term surveillance is critical as metastases can emerge years post-initial treatment.

Abstract