MMFT-Simulator: A tailored microfluidics simulator

The MMFT-Simulator is a unified framework for simulating microfluidic devices, explicitly designed to leverage microscale phenomena across multiple abstraction levels. It integrates multiple simulation methods within a single, modular architecture, covering diverse physical phenomena and enabling both high-fidelity and rapid simulations. Its matrix-based design allows new abstraction levels, physical phenomena, or methods to be incorporated with minimal effort, promoting extensibility and reuse. By consolidating diverse computational approaches into a coherent, user-friendly environment, the MMFT-Simulator advances microfluidic modeling, facilitating reproducible design, efficient prototyping, and the development of increasingly complex multi-physics simulations. • Unified framework for multi-level microfluidic simulation. • Matrix-based architecture integrates abstraction and physics. • Supports abstract, hybrid, and CFD-based modeling. • Covers flow, concentration, droplet, and membrane platforms. • Enables efficient design via fidelity–runtime trade-offs.