Prediction of Outcomes of Brain Irradiation in Correlation with Molecular Subtypes in Patients with Metastatic Breast Cancer

Key Points

• The central aim is to identify prognostic factors that impact survival in breast cancer patients with brain metastases and to propose a scoring system for treatment decisions.
• Analysis of molecular subtypes and clinical characteristics in patients with metastatic breast cancer.
• Identification of key factors influencing survival outcomes.
• Development of a scoring system to aid in radiotherapy decision-making.
• HER2-positive and triple-negative subtypes have the poorest survival rates.
• The proposed scoring system helps guide radiotherapy decisions based on patient-specific factors.
• Further validation is necessary to confirm the scoring system's accuracy and utility.

Abstract