Does federated diagnostic meta-analysis produce HEART score performance estimates comparable to centralized patient-level data in emergency department chest pain patients?
Patients presenting to the Emergency Department with chest pain
Federated diagnostic meta-analysis of HEART score performance
Centralized patient-level data analysis
HEART score performance estimates
Federated meta-analysis provides a scalable, privacy-preserving approach for multicenter evaluation of ED risk-stratification tools like the HEART score.
Federated diagnostic meta-analysis produced HEART score performance estimates closely aligned with those obtained from centralized patient-level data. This approach enabled scalable, privacy-preserving multicenter evaluation of ED risk-stratification tools while accommodating heterogeneity across practice settings.
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Hao Wang
Eric Chou
Richard D. Robinson
Academic Emergency Medicine
Wake Forest University
Baylor University Medical Center
Baylor Scott & White All Saints Medical Center
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Wang et al. (Wed,) studied this question.
www.synapsesocial.com/papers/69d894ce6c1944d70ce05c21 — DOI: https://doi.org/10.1111/acem.70284