What question did this study set out to answer?

The aim is to evaluate long-term survival outcomes associated with multimodal management of colorectal liver metastases.

April 10, 2026Open Access

Two Decades of Multimodal Management of Colorectal Liver Metastases With Long‐Term Outcomes

Key Points

The aim is to evaluate long-term survival outcomes associated with multimodal management of colorectal liver metastases.
Analysis of a real-world cohort undergoing liver resection for colorectal liver metastases.
Utilization of long-term follow-up data spanning 10 years.
Assessment of the evolving treatment paradigms over two decades.
One-third of patients achieved long-term survival post-liver resection.
Demonstrated the complex contribution of non-surgical treatments.
Highlighted the necessity for personalized management strategies for improved outcomes.

Abstract

One-third of patients who undergo liver resection for CRLM achieve long-term survival. While multi-modal therapy was commonly used, determining the specific contribution of non-surgical treatments is challenging in a real-world cohort where treatment paradigms evolved over time. This study provides rare 10-year follow-up data and reinforces the need for ongoing refinement of personalised management strategies for CRLM.

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Discussion

Authors

Ali Mohtashami

Prajwol Shrestha

Sharon C.‐A. Chen

Journals

ANZ Journal of Surgery

Actions

Institutions

The University of Sydney

Royal North Shore Hospital

Northern Sydney Local Health District

References and Citations

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Building similarity graph...

Analyzing shared references across papers

Two Decades of Multimodal Management of Colorectal Liver Metastases With Long‐Term Outcomes

Key Points

Abstract

Citation Network

Connected Papers

Discussion

Authors

Journals

Actions

Institutions

References and Citations

Citation Network

Connected Papers

Discussion

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