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Therapeutic Targeting of S100A2 Enhances Chemotherapy Efficacy in vitro in Oral Cancer | Synapse

April 10, 2026Open Access

Therapeutic Targeting of S100A2 Enhances Chemotherapy Efficacy in vitro in Oral Cancer

Key Points

The aim is to investigate S100A2 as a therapeutic target for enhancing chemotherapy effectiveness in oral cancer.
In vitro experiments assessing S100A2 targeting
Evaluation of chemotherapy response
Analysis of drug resistance mechanisms
Targeting S100A2 significantly improves chemotherapy response
Potential reduction in drug resistance observed
Encourages further studies for clinical application

Abstract

These findings position S100A2 as a potential therapeutic target for overcoming drug resistance and improving treatment efficacy in OSCC. Further mechanistic studies and in vivo validation are warranted to explore its translational relevance in clinical oncology.

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Authors

M

Manish Kumar

C

Chandra Prasad

C

Chitrakshi Chopra

Journals

Asian Pacific Journal of Cancer Prevention

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Institutions

All India Institute of Medical Sciences

References and Citations

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Cite this study

Kumar et al. (Wed,) studied this question.

www.synapsesocial.com/papers/69d895046c1944d70ce0606b — DOI: https://doi.org/10.31557/apjcp.2026.27.4.1351