What question did this study set out to answer?

The research aims to explore the factors influencing the implementation of GnRH analogs for ovarian protection in women receiving chemotherapy in Japan.

April 10, 2026Open Access

Nationwide Survey of Institutional Factors Related to the Use of Gonadotropin‐Releasing Hormone Analogs for Ovarian Protection in Women Receiving Chemotherapy in Japan

Key Points

The research aims to explore the factors influencing the implementation of GnRH analogs for ovarian protection in women receiving chemotherapy in Japan.
Conducted a nationwide survey across various healthcare institutions in Japan
Assessed awareness and reported usage of GnRH agonists
Analyzed institutional characteristics and policy-related factors influencing decisions
High awareness of GnRH recommendations but low clinical implementation
Institutional characteristics linked to reported use of GnRH agonists
Identified a gap between clinical practice and available evidence for fertility preservation

Abstract

Despite high awareness of recommendations for GnRH agonists, the clinical implementation of GnRH analogs for ovarian protection remains limited in Japan. Institutional characteristics and policy-related factors were associated with reported GnRH agonist use, although causal relationships cannot be inferred. These findings highlight a gap between current clinical practice and available evidence and underscore the need for careful evaluation of the role of GnRH analogs within existing fertility preservation frameworks.

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Discussion

Authors

Shina Sakaguchi

Eishin Nakamura

Haipeng Huang

Journals

Journal of obstetrics and gynaecology research

Actions

Institutions

Jichi Medical University

Saitama Medical University

National Center For Child Health and Development

References and Citations

Connected Papers

Building similarity graph...

Analyzing shared references across papers

Nationwide Survey of Institutional Factors Related to the Use of Gonadotropin‐Releasing Hormone Analogs for Ovarian Protection in Women Receiving Chemotherapy in Japan

Key Points

Abstract

Citation Network

Connected Papers

Discussion

Authors

Journals

Actions

Institutions

References and Citations

Citation Network

Connected Papers

Discussion

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