Mapping the maternal–fetal interface through pregnancy in high resolution

Key Points

• To create a detailed map of the cell types and interactions at the maternal-fetal interface during pregnancy.
• Developed a high-resolution map of individual cells at the placenta-uterus junction
• Characterized known and unknown cell types involved in placental–uterine connections
• Analyzed cell interactions that contribute to pregnancy complications
• Identified specific cell–cell interactions at the maternal-fetal interface
• Pinpointed vulnerable cell types linked to common pregnancy complications
• Expanded knowledge of placental cell types and states

Abstract