The JNK2-microbiome axis modulates gut barrier integrity through microbial acetate

Key Points

• To investigate how post-weaning milk supplementation affects gut microbiome and barrier integrity.
• Utilized immediate post-weaning milk supplementation
• Monitored gut microbiome composition
• Assessed gut barrier integrity through various metrics
• Milk supplementation preserved a beneficial gut microbiome, notably D. newyorkensis
• Gut barrier integrity was enhanced with supplementation
• A one-week delay in supplementation eliminated the protective effects

Abstract