A Comparative In vitro Analysis Of Remineralising Efficacy of Commercially Available Toothpastes and Mouthwashes in Demineralised Primary Teeth using Diagnodent

Abstract Background: The early identification and noninvasive treatment of developing lesions with new remineralizing agents is becoming the paradigm for caries control. This study compares the remineralization potential of commercially available agents (toothpaste and mouthwash) on white spot lesions (WSLs) in primary teeth that are artificially created. Materials and Methods: In this in vitro randomized trial, eighty extracted or exfoliated primary teeth were randomly divided into eight groups: Group A–Cheerio toothpaste (Sodium monofluorophosphate MFP), Group B–Amflor toothpaste (Amine fluoride), Group C–Toothmin toothpaste (Calcium sucrose phosphate), Group D –Dent91 toothpaste (NanoHydroxyapatite), Group E–Aloe HA toothpaste (Aloe Vera), Group F–Dabur Meswak herbal toothpaste (Meswak), Group G –Kidodent Mouthwash (Sodium fluoride), and Group H–Hiora Mouthwash (Meswak). WSLs were artificially induced, and samples were treated with the respective agents. DIAGNOdent readings were measured before demineralization, after remineralization, and at baseline. Results: All groups showed significant improvement within groups in DIAGNOdent values after remineralization ( P < 0.001). However, intergroup comparisons indicated that the calcium sucrose phosphate group, followed by the sodium MFP group, demonstrated a more significant remineralization potential than the other groups. Conclusion: Although all tested agents demonstrated effective remineralization potential, with comparable differences among them, calcium sucrose phosphate, closely followed by sodium monoflurophosphate, exhibited greater remineralizing potential, indicating its suitability for noninvasive management of early carious lesions in primary teeth.