A Comprehensive Study of Novel Pregnenolone-Isoxazole Hybrids as Selective Inducers of Mitochondrial Apoptosis in Breast Cancer Cells

Key Points

• The study aims to investigate the effects of pregnenolone-isoxazole hybrids on mitochondrial apoptosis in breast cancer cells.
• Developed novel pregnenolone-isoxazole hybrid compounds
• Assessed their impact on apoptosis induction
• Examined mitochondrial dysfunction in breast cancer cells
• Identified effective inducers of mitochondrial apoptosis
• Demonstrated disruption of mitochondrial function in cancer cells
• Showed potential for targeting multiple cancer-related pathways

Abstract