A 77-year-old man with a remote history of renal cell carcinoma (RCC) presenting with gait disturbance
[18F]FP-CIT PET/CT
Detection of brain metastasessurrogate
Hypervascular metastases such as RCC may exhibit cortical [18F]FP-CIT uptake, warranting cautious interpretation and correlation with anatomic imaging.
A 77-year-old man with a remote history of renal cell carcinoma (RCC) presented with gait disturbance and underwent delayed 18FFP-CIT PET/CT to evaluate Parkinsonism. The scan showed focal uptake in the temporoparietal and insular cortices with a focal striatal photopenic defect. Brain MRI confirmed enhancing metastases corresponding to the cortical foci and attributed the striatal abnormality to chronic infarction. Hypervascular metastases such as RCC may exhibit cortical 18FFP-CIT uptake, possibly from increased perfusion and/or altered blood-brain barrier permeability, reflecting nonspecific tracer retention. Therefore, cortical uptake warrants cautious interpretation and appropriate correlation with clinical history and anatomic imaging for differential diagnosis.
Building similarity graph...
Analyzing shared references across papers
Loading...
Sang Jun Byun
Byungwook Choi
Clinical Nuclear Medicine
Keimyung University
Catholic University of Daegu
Building similarity graph...
Analyzing shared references across papers
Loading...
Byun et al. (Tue,) studied this question.
www.synapsesocial.com/papers/69d895d86c1944d70ce06f9c — DOI: https://doi.org/10.1097/rlu.0000000000006466