(098) Impact of MHT on Social, Emotional and Occupational Aspects of Life

Abstract Introduction Beyond its associated symptoms, perimenopause and menopause has significant psychosocial implications. Many women report challenges in maintaining work performance, physical activity, and social participation, alongside strain in personal and family relationships. Despite this, the broader functional and emotional impacts of menopause remain under-recognised and undertreated in both research and clinical practice. Increasingly, there is recognition that effective menopause care and treatment should address not only symptom relief but also the social, emotional, and occupational consequences of this life stage. Objective This study aimed to evaluate the impact of menopause on patients’ quality of life, work, relationships, social engagement, and physical activity, and to assess changes following menopausal hormone therapy at a private menopause clinic in the United Kingdom. Methods We conducted a retrospective cohort study of new patients attending the clinic between March and May 2025. All participants completed a comprehensive menopause symptom and lifestyle impact questionnaire at baseline and at 3-month follow-up. The questionnaire assessed perceived impact across five domains - ability to work, relationship with spouse/partner, relationship with family, social life, and ability to remain active/exercise, using a Likert scale from 0 (not at all) to 3 (severe). Responses were compared between baseline and follow-up to determine change in perceived impact. Results Data was obtained for 674 patients. Across all domains, mean impact scores improved substantially from baseline to follow-up after 3 months of commencing menopausal hormone therapy. The largest relative improvements were observed in social life (mean 1.66 to 1.03) and ability to remain active/exercise (1.62 to 1.01). Nearly half of respondents reported improvements in their ability to work (48%) and relationships with their spouse/partner (49%), while 43–45% reported stability across most domains. The proportion reporting worsening was low across all areas (7–12%). Overall, these findings suggest broad quality-of-life benefits within just 3 months of initiating hormone management during the menopause. Conclusions Comprehensive and personalised hormone treatment was associated with marked improvements in multiple dimensions of daily functioning and relationships. These results highlight the importance of holistic, individualised care approaches that address not only physical symptoms but also the wider psychosocial impacts of menopause. Disclosure No.