“Relapsing Polychondritis Revisited: Enhanced Lesion Detection with Ga-68 FAPI PET/CT over F-18 FDG PET/CT”

Relapsing polychondritis is an autoimmune inflammatory disorder characterised by immune-mediated destruction of cartilaginous and proteoglycan-rich tissues, driven by autoantibodies against type II collagen and activation of macrophages and fibroblasts. We report a case of a 50-year-old female who presented with multisystemic involvement and nonspecific tracheal inflammation. F-18 FDG (Fluorodeoxy glucose) and Ga-68 FAPI PET/CT (Fibroblast Activating Protein Inhibitor) were done for evaluation. Ga-68 FAPI PET/CT showed enhanced lesion detection over F-18 FDG PET/CT in this case of Relapsing Polychondritis.