These findings reveal, for the first time, that acute EtOH produces sex-specific effects on GABAergic transmission in the CeL, enhancing inhibitory signaling in males but not females. This pattern mirrors previous observations in the CeM and underscores the importance of including both sexes in alcohol research. Understanding the mechanisms underlying these differences may inform the development of sex-specific treatments for alcohol use disorder.
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Emaya Moss
Enkhzul Batsaikhan
Samantha Amsden
Alcohol Clinical and Experimental Research
University of Tennessee Health Science Center
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Moss et al. (Wed,) studied this question.
www.synapsesocial.com/papers/69d896046c1944d70ce07362 — DOI: https://doi.org/10.1111/acer.70290