What question did this study set out to answer?

The study aims to examine the relationship between erythropoietin receptor expression and tubular injury severity in acute kidney injury.

April 10, 2026Open Access

Erythropoietin receptor upregulation is associated with tubular injury severity in human acute kidney injury

Key Points

The study aims to examine the relationship between erythropoietin receptor expression and tubular injury severity in acute kidney injury.
Assessment of EPOR expression in renal tubular epithelial cells
Correlation analysis with histopathological injury severity
Evaluation of selected clinical parameters
EPOR expression is significantly upregulated in acute kidney injury cases
Stronger EPOR levels are associated with greater histopathological injury severity
Findings suggest EPOR could serve as a marker for tubular stress

Abstract

EPOR expression is upregulated in renal tubular epithelial cells in human AKI and is closely associated with histopathological injury severity and selected clinical parameters, highlighting that EPOR may serve as a marker of tubular stress and injury severity in AKI.

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Discussion

Authors

Kun Xie

G Zhou

Mengjin Li

Journals

Renal Failure

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Institutions

Augusta University

Shanghai Changzheng Hospital

Northern Jiangsu People's Hospital

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Erythropoietin receptor upregulation is associated with tubular injury severity in human acute kidney injury

Key Points

Abstract

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Connected Papers

Discussion

Authors

Journals

Actions

Institutions

References and Citations

Citation Network

Connected Papers

Discussion

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