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Preponderance of 9-Item Patient Health Questionnaire (PHQ-9) Evidence—Reply | Synapse

April 10, 2026

Preponderance of 9-Item Patient Health Questionnaire (PHQ-9) Evidence—Reply

Key Points

The aim is to address important comments regarding the PHQ-9's effectiveness in assessing depression.
Responding to commentary on PHQ-9 use in clinical settings
Reviewing psychometric evaluation of the PHQ-9
Discussing implications of global utilization.
Affirmation of PHQ-9's widespread application
Recognition of its clinical validity in various populations
Clarification of psychometric strengths and limitations.

Abstract

In Reply We thank Kroenke for his thoughtful comments on our recently published article.1 Given the widespread global use of the 9-item Patient Health Questionnaire (PHQ-9), we are pleased to respond to several important points raised in his commentary.

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Cite this study

Razum et al. (Wed,) studied this question.

www.synapsesocial.com/papers/69d896566c1944d70ce07b24 — DOI: https://doi.org/10.1001/jamapsychiatry.2026.0546

Authors

J

Josip Razum

M

Margarita Panayiotou

Z

Zachary D. Cohen

Journals

JAMA Psychiatry

Actions

Institutions

University of Arizona

University of Manchester

References and Citations

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