Treatment with a multidrug-resistant tuberculosis regimen, antiretroviral therapy, and low-dose steroids led to the clinical and radiological resolution of necrotic pericardial masses in a patient with HIV.
Case Report
No
30-year-old male patient with multidrug-resistant (MDR) tuberculous pericarditis (TP) on anti-tuberculous therapy and retroviral disease (HIV) on anti-retroviral treatment, presenting with dyspnea on exertion grade I-II.
Highlights a rare presentation of necrotic pericardial masses in an immunocompromised patient with multidrug-resistant tuberculous constrictive pericarditis.
Tuberculous pericarditis (TP) continues to pose a significant challenge in countries where tuberculosis (TB) is endemic. Human immunodeficiency virus (HIV)-associated TP tends to be a more severe condition, often causing a higher degree of heart muscle damage. The presence of HIV significantly alters the progression and outcomes of TP Immunocompromised individuals are more prone to developing constrictive pericarditis and have a notably higher mortality rate compared to those with normal immune function. Additionally, the dual infection with HIV and TB has introduced several unresolved issues in understanding its full clinical impact. We present a case report of a 30-year-old male patient, a known and follow-up case of multidrug-resistant (MDR) TP on anti-tuberculous therapy (ATT) and retroviral disease (RVD) on anti-retroviral treatment (ART) with complaints of dyspnea on exertion grade I-II.
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Anagha Rajeev Joshi
Sayali Mangal Dhote
Niranjana Sanjay Dhanrajani
Annals of the National Academy of Medical Sciences (India)
Lokmanya Tilak Municipal General Hospital and Lokmanya Tilak Municipal Medical College
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Joshi et al. (Wed,) conducted a case report in Tuberculous constrictive pericarditis with HIV co-infection (n=1). MDR-TB regimen, antiretroviral therapy (ART), and steroids was evaluated on Clinical and radiological resolution. Treatment with a multidrug-resistant tuberculosis regimen, antiretroviral therapy, and low-dose steroids led to the clinical and radiological resolution of necrotic pericardial masses in a patient with HIV.
www.synapsesocial.com/papers/69d896676c1944d70ce07c45 — DOI: https://doi.org/10.25259/anams_99_2025