What question did this study set out to answer?

The aim was to investigate the association between antidepressant use and pneumonia hospitalisation in older adults.

April 10, 2026

Antidepressants and risk of pneumonia in older adults: a nationwide self-controlled case series

Key Points

The aim was to investigate the association between antidepressant use and pneumonia hospitalisation in older adults.
Utilized a nationwide self-controlled case series design

Structured PICO

Does antidepressant use increase the risk of pneumonia hospitalisation in older adults?

Population

older adults

Intervention

Antidepressant use

Comparator

self-controlled (periods without antidepressant use)

Outcome

pneumonia hospitalisationsafety

Antidepressant use in older adults is associated with an increased risk of pneumonia hospitalization, highlighting the need for routine medication reviews.

Abstract

Antidepressant use was associated with an increased pneumonia hospitalisation in older adults. The risk was further elevated in patients with neurologic conditions or a high anticholinergic/sedative burden, highlighting the need for individualised prescriptions and routine medication reviews.

Connected Papers

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Discussion

Authors

Jinyoung Jeon

Min Jung Geum

Young‐Mi Ah

Journals

Age and Ageing

Actions

Institutions

Yonsei University

Hanyang University

Yeungnam University

References and Citations

Connected Papers

Building similarity graph...

Analyzing shared references across papers

Antidepressants and risk of pneumonia in older adults: a nationwide self-controlled case series

Key Points

Structured PICO

Abstract

Citation Network

Connected Papers

Discussion

Authors

Journals

Actions

Institutions

References and Citations

Citation Network

Connected Papers

Discussion

Cite this study