What question did this study set out to answer?

To evaluate the effectiveness of preoperative pan-immune-inflammation value as a biomarker for malignancy risk in thyroid nodules with atypia of undetermined significance.

April 10, 2026

Preoperative Pan-Immune-Inflammation Value as a Predictor of Malignancy in Thyroid Nodules With Atypia of Undetermined Significance

Key Points

To evaluate the effectiveness of preoperative pan-immune-inflammation value as a biomarker for malignancy risk in thyroid nodules with atypia of undetermined significance.
Evaluated the pan-immune-inflammation value in thyroid nodules classified as AUS/FLUS.
Conducted assessments of malignancy risk based on PIV scores.
Suggested further studies to confirm findings and establish cutoff values.
PIV demonstrated potential as an adjunctive biomarker for malignancy stratification.
Utilization of PIV may aid in reducing unnecessary surgical interventions.
Further prospective studies are needed to validate the findings.

Abstract

Preoperative PIV may serve as a simple and readily available adjunctive biomarker to assist in malignancy risk stratification of AUS/FLUS thyroid nodules. Its use may contribute to more informed surgical decision-making and help reduce unnecessary surgical interventions. Prospective studies are warranted to validate these findings and to determine clinically relevant cutoff values.

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Discussion

Authors

Tuğçe Taşar Yildirim

Yavuz S.S. Yildirim

Journals

Journal of Craniofacial Surgery

Actions

Institutions

Sağlık Bilimleri Üniversitesi

Elazığ Eğitim ve Araştırma Hastanesi

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Preoperative Pan-Immune-Inflammation Value as a Predictor of Malignancy in Thyroid Nodules With Atypia of Undetermined Significance

Key Points

Abstract

Citation Network

Connected Papers

Discussion

Authors

Journals

Actions

Institutions

References and Citations

Citation Network

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Discussion

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