Food Allergy‐Induced Systemic Immune Alterations Affect Tumor Progression in a CT26 Colon Adenocarcinoma Mouse Model

Key Points

• This research examines how food allergies can influence tumor growth and immune responses.
• Developed an in vivo model for studying food allergies and tumors.
• Evaluated the effects of systemic allergic responses on tumor behavior.
• Assessed immune activation, apoptosis, and metabolic changes in the tumor environment.
• Allergic responses were shown to activate immune pathways related to tumor growth.
• Induced apoptosis was observed in tumor cells influenced by allergic responses.
• Significant alterations in inflammation and metabolism were noted, affecting tumor progression.

Abstract