What does this research mean for the field?

Exposure to paracetamol (acetaminophen) during pregnancy is not associated with adverse neurodevelopmental outcomes, including autism spectrum disorder, in children. Novelty: ClaimNovelty.SYNTHESIS. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

To determine the relationship between prenatal exposure to acetaminophen and child neurodevelopmental disorders.

April 10, 2026

Meta‐analysis finds no link between acetaminophen exposure and child neurodevelopmental disorders

Key Points

To determine the relationship between prenatal exposure to acetaminophen and child neurodevelopmental disorders.
Conducted a systematic review of existing studies
Performed a meta-analysis excluding unadjusted analyses
Evaluated outcomes related to neurodevelopmental disorders, including autism spectrum disorder
Found no significant association between acetaminophen exposure and neurodevelopmental disorders in children
Indicated that previous concerns regarding acetaminophen and autism spectrum disorder may be unfounded

Abstract

A systematic review and meta‐analysis has found no association between exposure to paracetamol (acetaminophen) during pregnancy and adverse neurodevelopmental outcomes in children, including autism spectrum disorder. The investigators' review excluded all studies that used unadjusted analyses.

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Journals

The Brown University Psychopharmacology Update

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Building similarity graph...

Analyzing shared references across papers

Meta‐analysis finds no link between acetaminophen exposure and child neurodevelopmental disorders

Key Points

Abstract

Citation Network

Connected Papers

Discussion

Journals

Actions

References and Citations

Citation Network

Connected Papers

Discussion

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