Effective extraction and determination of 9 β-lactams in water and milk samples by a novel magnetic covalent organic framework combined with UPLC-MS/MS

Key Points

• To design and synthesize a magnetic covalent organic framework for extracting β-lactams from water and milk samples.
• Synthesis of Fe 3 O 4 @SiO 2 @Ap-COF as adsorbent
• Utilization of magnetic solid-phase extraction (MSPE)
• Application of UPLC-MS/MS for detection
• Successfully extracted 9 different β-lactams from the samples
• Demonstrated efficient adsorption capability of the magnetic framework
• Provided clear evidence of β-lactam presence in analyzed samples

Abstract