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April 11, 2026Quality & Quantity0 citationsOpen Access

An extension to the Johnson-Neyman test for generalized linear models with curvilinear effects

PGPaolo GirardiLMLibera Ylenia MastromatteoSSSara Scrimin

Key Result

Cardiac vagal tone exhibited an inverted U-shaped association with the likelihood of cooperation that was significant only in younger children aged 6 to 7.57 years.

Key Points

  • The research aims to extend the Johnson-Neyman test to evaluate moderator effects in curvilinear relationships within generalized linear models.
  • Developed a new approach for the Johnson-Neyman test to accommodate curvilinear relationships.
  • Conducted a simulation study to validate the proposed method.
  • Applied the method to real data examining cardiac vagal tone and cooperation in school-aged children.
  • Validated the curvilinear extension through simulation studies showing its effectiveness.
  • Demonstrated that the new method yields more accurate inferences compared to the conventional pick-a-point approach.

Study Design

Type

Observational (n=111)

Structured PICO

P
Population
School-aged children (used as a real data set application to investigate the relationship between cardiac vagal tone and cooperation)

Provides a statistical extension to the Johnson-Neyman test for evaluating moderators in curvilinear relationships, applicable to generalized linear models.

Main Result

p-value: p=<0.001

Limitations

  • Relies on a correctly specified functional form (quadratic-by-linear interaction structure); higher order relationships may yield biased results.
  • Observational data can exhibit uneven covariate distributions, making estimates of critical points imprecise when far from the center.
  • Vulnerable to outliers, measurement errors, and violations of model assumptions.

Abstract

The Johnson-Neyman technique is widely used in observational research to identify regions of a moderator variable where the linear relationship between a predictor and an outcome variable is statistically significant. In practice, moderation is often assessed using the pick-a-point approach, which examines effects at arbitrarily chosen moderator values and can produce incomplete or misleading inferences, especially when the underlying relationships are curvilinear. Few procedures have been proposed to address the need to evaluate the effect of moderators in curvilinear relationships between outcome and predictor considering quadratic terms or more complex relationships. However, such curvilinear relationships are fundamental in psychology, medicine, economics, and other disciplines to better explain phenomena where outcomes do not change in a strictly linear manner with respect to influencing variables. This paper proposes a new approach to extend the Johnson-Neyman test to evaluate the effect of a moderator in curvilinear relationships and provides accessible tools for its implementation alongside the conventional pick-a-point approach. This extension covers both linear regression and generalized linear regression models. The curvilinear extension of the Johnson-Neyman method is validated by a simulation study and applied to a real data set to investigate the relationship between cardiac vagal tone and cooperation in school-aged children, taking into account the moderating role of age.

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Cite This Study

Girardi et al. (2026) reported an observational. Cardiac Vagal Tone (CVT) was evaluated on Likelihood of cooperation (sum of cooperative trials) (p=<0.001). Cardiac vagal tone exhibited an inverted U-shaped association with the likelihood of cooperation that was significant only in younger children aged 6 to 7.57 years.

synapsesocial.com/papers/69d9e55278050d08c1b757eahttps://doi.org/10.1007/s11135-026-02748-4
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