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April 11, 2026Blood Research0 citationsOpen Access

Autologous bone marrow transplantation in non-hodgkin lymphoma patients following different conditioning regimens: an 11-year single-center quasi-experimental study

SSSahar Tavakoli ShirajiMBMohammad BiglariSRSoroush Rad

Key Points

  • To assess the impact of different conditioning regimens on survival outcomes in NHL patients undergoing autologous stem cell transplantation (ASCT).
  • Quasi-experimental study design at a single center
  • Inclusion of NHL patients undergoing ASCT
  • Comparison of survival outcomes with and without carboplatin in the EAM regimen
  • No significant difference in survival outcomes observed with the addition of carboplatin to the EAM regimen
  • Findings suggest that carboplatin may not enhance survival in this population

Abstract

Our real-world data indicate that the addition of carboplatin to the EAM conditioning regimen does not significantly affect survival outcomes for patients with NHL undergoing ASCT.

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Cite This Study

Shiraji et al. (2026) studied this question.

synapsesocial.com/papers/69d9e5ec78050d08c1b7616chttps://doi.org/10.1007/s44313-026-00131-8
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Toxicity and efficacy of four carmustine-substituted conditioning regimens followed by autologous stem cell transplantation in lymphoma: a real-world comparative study2026
  2. 2Optimized BEAC conditioning regimen improves clinical outcomes of autologous hematopoietic stem cell transplantation in non-Hodgkin lymphomas2024 · 1 citations
  3. 3Clinical and safety outcomes of BeEAM (Bendamustine, Etoposide, Cytarabine, Melphalan) versus CEM (Carboplatin, Etoposide, Melphalan) in lymphoma patients as a conditioning regimen before autologous hematopoietic cell transplantation2024 · 1 citations
  4. 4Autologous hematopoietic stem cell transplantation conditioning regimens and chimeric antigen receptor T cell therapy in various diseases2024 · 1 citations
  5. 5The notable outcomes of modified thiotepa-based conditioning followed by autologous stem cell transplantation in primary central nervous system lymphomas: A real-life pilot study2024