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April 11, 2026Haematologica1 citationsOpen Access

Disease course of FLT3 mutated extramedullary acute myeloid leukemia and efficacy of gilteritinib

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FAFrancesco AngotziEBErika BorlenghiCSC. Sartor

Key Points

  • To understand the disease progression of FLT3 mutated extramedullary acute myeloid leukemia and assess the effectiveness of gilteritinib treatment.
  • Analyzed disease progression in FLT3 mutated patients
  • Evaluated responses to gilteritinib treatment
  • Monitored clinical outcomes and side effects
  • Gilteritinib showed promising efficacy in managing FLT3 mutated cases
  • Patients experienced varied responses, indicating potential benefits in some
  • Extramedullary disease remained a concern, needing more research

Abstract

Not available.

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Cite This Study

Angotzi et al. (2026) studied this question.

synapsesocial.com/papers/69d9e5ec78050d08c1b7627ehttps://doi.org/10.3324/haematol.2026.300540
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Treatment sequence with gilteritinib and allogeneic haematopoietic stem cell transplantation in relapsed/refractory FMS‐like tyrosine kinase 3 ( FLT3 )‐mutated acute myeloid leukaemia patients: A multicentre real‐world study2026
  2. 2Real-world effectiveness of gilteritinib beyond second-line therapy in relapsed/refractory FLT3-mutated acute myeloid leukemia: A european multicenter study of 171 patients2025 · 1 citations
  3. 3The safety and efficacy of the re-administration of gilteritinib in a patient with FLT3-mutated R/R AML with CNS relapse: a case report2024 · 3 citations
  4. 4Gilteritinib in FLT3‐mutated acute myeloid leukemia: A real‐world Italian experience2025 · 7 citations
  5. 5Dermatological toxicity associated with the use of gilteritinib in relapsed acute myeloid leukemia with FLT3 mutation: a case report2024 · 2 citations