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April 11, 2026A&A Practice0 citations

Severe Hypercapnia During Jet Ventilation Causes Reversible Frontal EEG Suppression in the Setting of Total Intravenous Anesthesia: A Case Report

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LPLuu N. PhamJNJacques NobleCGChristian S. Guay

Key Points

  • To investigate the effects of severe hypercapnia on EEG during jet ventilation in a patient under anesthesia.
  • Described a case of a 23-year-old man undergoing surgery under total intravenous anesthesia.
  • Monitored frontal EEG trends during periods of jet ventilation.
  • Performed arterial blood gas analysis to assess carbon dioxide levels.
  • Reintroduced controlled ventilation after identifying severe hypercapnia.
  • EEG showed declining spectral edge frequency and increasing burst suppression during hypercapnia.
  • Confirmed arterial blood gas readings indicated severe hypercapnia at 133 mm Hg.
  • Following reintubation and controlled ventilation, EEG and hemodynamic parameters normalized.

Abstract

Jet ventilation can limit reliable capnography, increasing the risk of unrecognized carbon dioxide (CO 2 ) retention during airway surgery. We describe a 23-year-old man undergoing tracheal costochondral graft surgery under propofol–remifentanil total intravenous anesthesia with processed frontal electroencephalography (EEG) monitoring. During prolonged apneic jet ventilation, EEG trends showed declining spectral edge frequency and increasing burst suppression with hypertension. Arterial blood gas confirmed severe hypercapnia (PaCO 2 133 mm Hg). After reintubation and controlled ventilation, hemodynamics and EEG indices normalized. This case highlights severe hypercapnia as a reversible cause of EEG suppression, supporting EEG as an adjunctive warning tool when hypercapnia is suspected.

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Cite This Study

Pham et al. (2026) studied this question.

synapsesocial.com/papers/69d9e67a78050d08c1b76eb0https://doi.org/10.1213/xaa.0000000000002193
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