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April 11, 2026ChemistrySelect

Basella alba Aqueous Extract Characterization and Bioactivity Analysis Against Colorectal Cancer

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Authors

AAAsha Monica AlexHSHebslin Ruth SPVP. Vijayalakshmi

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Overview

Research evaluates the anticancer potential of Basella alba extract in colorectal cancer, suggesting it may help in treatment.

Key Points

  • The aim is to analyze the anticancer potential of Basella alba leaf extract against colorectal cancer.
  • Characterization of phytochemicals using Gas Chromatography-Mass Spectrometry (GC-MS).
  • Assessment of antioxidant activity via DPPH and other assays.
  • Evaluation of apoptotic effects on HCT-116 cells.
  • Gene expression analysis of BAX, CASPASE-3, and BCL2.
  • Identified significant antioxidant activity with varying IC50 values.
  • Demonstrated dose and time-dependent apoptosis in cancer cells.
  • Confirmed apoptosis through DAPI staining and flow cytometry.
  • Found regulation of key genes linked to cell cycle and apoptosis.

Cite This Study

Alex et al. (2026) studied this question.

synapsesocial.com/papers/69d9e6b078050d08c1b76f7dhttps://doi.org/10.1002/slct.202507434
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