MRI measurement of the delayed secondary ischaemic injury following endovascular thrombectomy: results from the REPERFUSE-NA1 study.

Key Points

• To evaluate the feasibility of whole-brain volume loss as a marker for delayed secondary ischaemic injury.
• Conducted MRI assessments of brain volume following endovascular thrombectomy.
• Measured changes in whole-brain volume to assess ischaemic injury.
• Applied MR-based markers to evaluate the implications for neuroprotectant trials.
• Whole-brain volume loss was established as a viable measurement method.
• Findings align with previous studies on ischaemic injury markers.
• Suggests that MR-based methods can enhance future clinical trials for neuroprotectants.