Structure–Activity Relationships of Morpholine-Modified Silicon(IV) Phthalocyanines as Potential Antidiabetic Agents

Key Points

• The aim is to explore the effectiveness of morpholine-modified silicon(IV) phthalocyanines as potential agents for treating type 2 diabetes.
• Synthesis of morpholine-modified silicon(IV) phthalocyanines.
• Evaluation of their biological activity related to diabetes.
• Comparison of effectiveness against existing antidiabetic drugs.
• Certain compounds demonstrated significant antidiabetic activity.
• Morpholine modifications enhanced biological effectiveness.
• The findings suggest a novel approach for diabetes management.

Abstract