Risk Factors of Disseminated Tumor Cells in the Bone Marrow of Patients With Angioimmunoblastic T‐Cell Lymphoma and Their Impact on Prognosis

Key Points

• This research investigates the relationship between disseminated tumor cells in bone marrow and patient prognosis in angioimmunoblastic T-cell lymphoma.
• Analyzed the presence of disseminated tumor cells in bone marrow samples.
• Evaluated prognostic factors including pleural effusion, CD3 expression, LDH, and hemoglobin levels.
• Correlated the loss of CD7 with overall survival.
• Disseminated tumor cells in bone marrow are linked to adverse prognosis.
• Pleural effusion is identified as an independent negative prognostic factor.
• Loss of CD7 is associated with shorter overall survival, while the combined profile predicts disease progression.

Abstract