Association between maternal thyroid function and adverse outcomes of pregnant women and offspring: evidence from an umbrella review

Key Points

• This review aims to explore the links between maternal thyroid function and various adverse outcomes for mothers and their offspring.
• Conducted an umbrella review of available studies on maternal thyroid dysfunction and outcomes.
• Evaluated a range of maternal and offspring outcomes related to thyroid function.
• Assessed the quality and certainty of evidence to understand its implications.
• Identified a broad range of adverse effects associated with maternal thyroid dysfunction.
• Found that overall certainty of the evidence was low, warranting more high-quality research.

Abstract