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September 1, 1991Annals of Internal Medicine3,525 citations

Survival in Patients with Primary Pulmonary Hypertension

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GDGilbert E. D’AlonzoRBRobyn J. BarstSAStephen M. Ayres

Key Points

  • Determine the relationship between mortality and right ventricular hemodynamic function in primary pulmonary hypertension.
  • Characterized mortality risk using an equation based on mean pulmonary artery pressure, mean right atrial pressure, and cardiac index.

Structured PICO

P
Population
Patients with Primary Pulmonary Hypertension
O
Outcome
Mortalityhard clinical

Right ventricular hemodynamic function (mean pulmonary artery pressure, mean right atrial pressure, and cardiac index) is closely associated with mortality in primary pulmonary hypertension.

Abstract

Mortality was most closely associated with right ventricular hemodynamic function and can be characterized by means of an equation using three variables: mean pulmonary artery pressure, mean right atrial pressure, and cardiac index. Such an equation, once validated prospectively, could be used as an adjunct in planning treatment strategies and allocating medical resources.

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Cite This Study

D’Alonzo et al. (1991) studied this question.

synapsesocial.com/papers/69dd11b95f91138675359c5chttps://doi.org/10.7326/0003-4819-115-5-343
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1PRIMARY PULMONARY HYPERTENSION IN PREGNANCY1964 · 113 citations
  2. 2Primary Pulmonary Hypertension1987 · 2,057 citations
  3. 3The Acute Administration of Vasodilators in Primary Pulmonary Hypertension: Experience from the National Institutes of Health Registry on Primary Pulmonary Hypertension1989 · 188 citations
  4. 4Regression of primary pulmonary hypertension.1976 · 92 citations
  5. 5Characteristics of surviving and nonsurviving patients with primary pulmonary hypertension1984 · 108 citations